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KMID : 0438219750120010293
Korea University Medical Journal
1975 Volume.12 No. 1 p.293 ~ p.298
Occurrence of Neutralizing Antibody to Japanese Encephalitis Virus in Bats


Abstract
Among the theories on the overwintering mechanism of Japanese encephalitis virus (JEV) in the temperate zone which has severe cold winter as in Korea, it has been suggested that bat, hibernating warm blooded animal, can pass with the virus.
Accordingly, for investigation of relationship between bat and Japanese encephalitis virus in Korea, 1,578 bats were collected and investigated for 5 years from 1965 to 1969. Results are as follows.
1. The species of bats distributed around Seoul were of three species W. murinus superans, R. ferrum-equinum and T. tralatitius abramus). The commonest species was V. murinus superans.
2. For 5 years from 1965 to 1969, with the internal organs and blood of 1, 578 bats, isolation of the virus in primary chick embryo cell culture had been attempted but in vain.
3. Sera of 519 bats in 1968, 279 in 1969 (total 798 bats) were investigated for neutralizing antibody to Japanese encephalitis virus in primary chick embryo cells. 93 bats (12.5%) were proven to have neutralizing antibody to Japanese encephalitis virus.
As above results, it was proven for the first time in Korea that mosquitoes with Japanese encephalitis virus had bitten bats.
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